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Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus

We analyzed the activation and function of dendritic cells (DCs) in the spleens of diseased, lupus-prone NZM2410 and NZB-W/F1 mice and age-matched BALB/c and C57BL/6 control mice. Lupus DCs showed an altered ex vivo costimulatory profile, with a significant increase in the expression of CD40, decrea...

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Detalles Bibliográficos
Autores principales:	Colonna, Lucrezia, Dinnall, Joudy-Ann, Shivers, Debra K, Frisoni, Lorenza, Caricchio, Roberto, Gallucci, Stefania
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526610/ https://www.ncbi.nlm.nih.gov/pubmed/16507174 http://dx.doi.org/10.1186/ar1911

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