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Targeting B cells in systemic lupus erythematosus: not just déjà vu all over again
Epratuzumab (anti-CD22) is a humanized monoclonal antibody that recognizes a pan-B-cell marker. It potentially downregulates B cell activity through negative signaling, as well as depleting B cells moderately. The uncontrolled series discussed by Dörner and colleagues in this issue of Arthritis Rese...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526641/ https://www.ncbi.nlm.nih.gov/pubmed/16732895 http://dx.doi.org/10.1186/ar1967 |