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Reduced Atherosclerotic Lesion Size in P-Selectin Deficient Apolipoprotein E-Knockout Mice Fed a Chow but Not a Fat Diet

Endothelial cells lining atherosclerotic, but not healthy sites, on human arteries express P-selectin. We investigated the role of P-selectin on the development of vascular lesions in an ApoE(−/−) male mice. Double-knockout (ApoE(−/−), P-selectin(−/−); DKO) were compared to single-knockout (ApoE(−/−...

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Detalles Bibliográficos
Autores principales:	Bourdillon, Marie-Claude, Randon, Jacques, Barek, Lydie, Zibara, Kazem, Covacho, Chantal, Poston, Robin N, Chignier, Elza, McGregor, John L
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526651/ https://www.ncbi.nlm.nih.gov/pubmed/16883052 http://dx.doi.org/10.1155/JBB/2006/49193

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