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Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins
BACKGROUND: Trisomy of human chromosome 21 (Chr21) results in Down's syndrome, a complex developmental and neurodegenerative disease. Molecular analysis of Down's syndrome, however, poses a particular challenge, because the aneuploid region of Chr21 contains many genes of unknown function....
Autores principales: | Hu, Yu-Hui, Warnatz, Hans-Jörg, Vanhecke, Dominique, Wagner, Florian, Fiebitz, Andrea, Thamm, Sabine, Kahlem, Pascal, Lehrach, Hans, Yaspo, Marie-Laure, Janitz, Michal |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526728/ https://www.ncbi.nlm.nih.gov/pubmed/16780588 http://dx.doi.org/10.1186/1471-2164-7-155 |
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