The Environmental Genome Project: functional analysis of polymorphisms.

The ultimate goal of the Environmental Genome Project is the improvement of human health on the basis of information about the variations in certain genes. The first phase of the project will involve the selection of the human genes and characterization of the alleles occurring in the American popul...

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Detalles Bibliográficos
Autor principal: Guengerich, F P
Formato: Texto
Lenguaje:English
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533131/
https://www.ncbi.nlm.nih.gov/pubmed/9637792
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author Guengerich, F P
author_facet Guengerich, F P
author_sort Guengerich, F P
collection PubMed
description The ultimate goal of the Environmental Genome Project is the improvement of human health on the basis of information about the variations in certain genes. The first phase of the project will involve the selection of the human genes and characterization of the alleles occurring in the American population. However, intelligent use of this information will require analysis of the relevance of the allelic differences. Epidemiology alone will not solve the problem, and mechanistic studies will be required. Factors to be considered in the design of functional analyses are considered in this commentary.
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spelling pubmed-15331312006-08-08 The Environmental Genome Project: functional analysis of polymorphisms. Guengerich, F P Environ Health Perspect Research Article The ultimate goal of the Environmental Genome Project is the improvement of human health on the basis of information about the variations in certain genes. The first phase of the project will involve the selection of the human genes and characterization of the alleles occurring in the American population. However, intelligent use of this information will require analysis of the relevance of the allelic differences. Epidemiology alone will not solve the problem, and mechanistic studies will be required. Factors to be considered in the design of functional analyses are considered in this commentary. 1998-07 /pmc/articles/PMC1533131/ /pubmed/9637792 Text en
spellingShingle Research Article
Guengerich, F P
The Environmental Genome Project: functional analysis of polymorphisms.
title The Environmental Genome Project: functional analysis of polymorphisms.
title_full The Environmental Genome Project: functional analysis of polymorphisms.
title_fullStr The Environmental Genome Project: functional analysis of polymorphisms.
title_full_unstemmed The Environmental Genome Project: functional analysis of polymorphisms.
title_short The Environmental Genome Project: functional analysis of polymorphisms.
title_sort environmental genome project: functional analysis of polymorphisms.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533131/
https://www.ncbi.nlm.nih.gov/pubmed/9637792
work_keys_str_mv AT guengerichfp theenvironmentalgenomeprojectfunctionalanalysisofpolymorphisms
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