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The traditional toxicologic paradigm is correct: dose influences mechanism.
Dose influences mechanism; and over a wide range of doses, one can envision that mechanism will change with changing dose. This basic concept in toxicology is juxtaposed with the biologic importance of maintaining normal DNA methylation status to provide the focus of this paper. The idea that altere...
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| Formato: | Texto |
| Lenguaje: | English |
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1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533292/ https://www.ncbi.nlm.nih.gov/pubmed/9539020 |