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Loss of KLP-19 polar ejection force causes misorientation and missegregation of holocentric chromosomes
Holocentric chromosomes assemble kinetochores along their length instead of at a focused spot. The elongated expanse of an individual holocentric kinetochore and its potential flexibility heighten the risk of stable attachment to microtubules from both poles of the mitotic spindle (merotelic attachm...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534123/ https://www.ncbi.nlm.nih.gov/pubmed/15452142 http://dx.doi.org/10.1083/jcb.200403036 |