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Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures

BACKGROUND: There are several evolutionarily unrelated and structurally dissimilar superfamilies of S-adenosylmethionine (AdoMet)-dependent methyltransferases (MTases). A new superfamily (SPOUT) has been recently characterized on a sequence level and three structures of its members (1gz0, 1ipa, and...

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Detalles Bibliográficos
Autores principales:	Kurowski, Michal A, Sasin, Joanna M, Feder, Marcin, Debski, Janusz, Bujnicki, Janusz M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153507/ https://www.ncbi.nlm.nih.gov/pubmed/12689347 http://dx.doi.org/10.1186/1471-2105-4-9

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