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Ku and the Stability of the Genome

Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the st...

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Detalles Bibliográficos
Autor principal: Friedl, Anna A.
Formato: Texto
Lenguaje:English
Publicado: 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153786/
https://www.ncbi.nlm.nih.gov/pubmed/12488585
http://dx.doi.org/10.1155/S1110724302201035
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author Friedl, Anna A.
author_facet Friedl, Anna A.
author_sort Friedl, Anna A.
collection PubMed
description Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the stability of the genome, both positively and negatively, in several ways. This article gives an overview on the role of Ku in determining the shape of the genome.
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spelling pubmed-1537862003-06-02 Ku and the Stability of the Genome Friedl, Anna A. J Biomed Biotechnol Review Article Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the stability of the genome, both positively and negatively, in several ways. This article gives an overview on the role of Ku in determining the shape of the genome. 2002 /pmc/articles/PMC153786/ /pubmed/12488585 http://dx.doi.org/10.1155/S1110724302201035 Text en Copyright © 2002, Hindawi Publishing Corporation
spellingShingle Review Article
Friedl, Anna A.
Ku and the Stability of the Genome
title Ku and the Stability of the Genome
title_full Ku and the Stability of the Genome
title_fullStr Ku and the Stability of the Genome
title_full_unstemmed Ku and the Stability of the Genome
title_short Ku and the Stability of the Genome
title_sort ku and the stability of the genome
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153786/
https://www.ncbi.nlm.nih.gov/pubmed/12488585
http://dx.doi.org/10.1155/S1110724302201035
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