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Ku and the Stability of the Genome
Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the st...
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Formato: | Texto |
Lenguaje: | English |
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2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153786/ https://www.ncbi.nlm.nih.gov/pubmed/12488585 http://dx.doi.org/10.1155/S1110724302201035 |
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author | Friedl, Anna A. |
author_facet | Friedl, Anna A. |
author_sort | Friedl, Anna A. |
collection | PubMed |
description | Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the stability of the genome, both positively and negatively, in several ways. This article gives an overview on the role of Ku in determining the shape of the genome. |
format | Text |
id | pubmed-153786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
record_format | MEDLINE/PubMed |
spelling | pubmed-1537862003-06-02 Ku and the Stability of the Genome Friedl, Anna A. J Biomed Biotechnol Review Article Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the stability of the genome, both positively and negatively, in several ways. This article gives an overview on the role of Ku in determining the shape of the genome. 2002 /pmc/articles/PMC153786/ /pubmed/12488585 http://dx.doi.org/10.1155/S1110724302201035 Text en Copyright © 2002, Hindawi Publishing Corporation |
spellingShingle | Review Article Friedl, Anna A. Ku and the Stability of the Genome |
title | Ku and the Stability of the Genome |
title_full | Ku and the Stability of the Genome |
title_fullStr | Ku and the Stability of the Genome |
title_full_unstemmed | Ku and the Stability of the Genome |
title_short | Ku and the Stability of the Genome |
title_sort | ku and the stability of the genome |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153786/ https://www.ncbi.nlm.nih.gov/pubmed/12488585 http://dx.doi.org/10.1155/S1110724302201035 |
work_keys_str_mv | AT friedlannaa kuandthestabilityofthegenome |