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pKD: re-designing protein pK(a) values

The pK(a) values in proteins govern the pH-dependence of protein stability and enzymatic activity. A large number of mutagenesis experiments have been carried out in the last three decades to re-engineer the pH-activity and pH-stability profile of enzymes and proteins. We have developed the pKD webs...

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Detalles Bibliográficos
Autores principales:	Tynan-Connolly, Barbara M., Nielsen, Jens Erik
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538816/ https://www.ncbi.nlm.nih.gov/pubmed/16845054 http://dx.doi.org/10.1093/nar/gkl192

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