SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes

SNPmasker is a comprehensive web interface for masking large eukaryotic genomes. The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs. In addition to the SNP masking, we also offer population-specific substitution of SNP alleles in gen...

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Detalles Bibliográficos
Autores principales: Andreson, Reidar, Puurand, Tarmo, Remm, Maido
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538889/
https://www.ncbi.nlm.nih.gov/pubmed/16845091
http://dx.doi.org/10.1093/nar/gkl125
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author Andreson, Reidar
Puurand, Tarmo
Remm, Maido
author_facet Andreson, Reidar
Puurand, Tarmo
Remm, Maido
author_sort Andreson, Reidar
collection PubMed
description SNPmasker is a comprehensive web interface for masking large eukaryotic genomes. The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs. In addition to the SNP masking, we also offer population-specific substitution of SNP alleles in genomic sequence according to SNP frequencies in HapMap Phase II data. The input to SNPmasker can be defined in chromosomal coordinates or inserted as a sequence. The sequences masked by our web server are most useful as a preliminary step for different primer and probe design tasks. The service is available at and is free for all users.
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spelling pubmed-15388892006-08-18 SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes Andreson, Reidar Puurand, Tarmo Remm, Maido Nucleic Acids Res Article SNPmasker is a comprehensive web interface for masking large eukaryotic genomes. The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs. In addition to the SNP masking, we also offer population-specific substitution of SNP alleles in genomic sequence according to SNP frequencies in HapMap Phase II data. The input to SNPmasker can be defined in chromosomal coordinates or inserted as a sequence. The sequences masked by our web server are most useful as a preliminary step for different primer and probe design tasks. The service is available at and is free for all users. Oxford University Press 2006-07-01 2006-07-14 /pmc/articles/PMC1538889/ /pubmed/16845091 http://dx.doi.org/10.1093/nar/gkl125 Text en © The Author 2006. Published by Oxford University Press. All rights reserved
spellingShingle Article
Andreson, Reidar
Puurand, Tarmo
Remm, Maido
SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title_full SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title_fullStr SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title_full_unstemmed SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title_short SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes
title_sort snpmasker: automatic masking of snps and repeats across eukaryotic genomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538889/
https://www.ncbi.nlm.nih.gov/pubmed/16845091
http://dx.doi.org/10.1093/nar/gkl125
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