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MicroFootPrinter: a tool for phylogenetic footprinting in prokaryotic genomes

Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the most conserved motifs in those homologous regions. This note describes web software that has been designed...

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Detalles Bibliográficos
Autores principales: Neph, Shane, Tompa, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538893/
https://www.ncbi.nlm.nih.gov/pubmed/16845027
http://dx.doi.org/10.1093/nar/gkl069
Descripción
Sumario:Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the most conserved motifs in those homologous regions. This note describes web software that has been designed specifically for this purpose in prokaryotic genomes, making use of the phylogenetic relationships among the homologous sequences in order to make more accurate predictions. The software is called MicroFootPrinter and is available at .