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pTARGET: a web server for predicting protein subcellular localization
The pTARGET web server enables prediction of nine distinct protein subcellular localizations in eukaryotic non-plant species. Predictions are made using a new algorithm [C. Guda and S. Subramaniam (2005) pTARGET [corrected] a new method for predicting protein subcellular localization in eukaryotes....
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538910/ https://www.ncbi.nlm.nih.gov/pubmed/16844995 http://dx.doi.org/10.1093/nar/gkl093 |
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author | Guda, Chittibabu |
author_facet | Guda, Chittibabu |
author_sort | Guda, Chittibabu |
collection | PubMed |
description | The pTARGET web server enables prediction of nine distinct protein subcellular localizations in eukaryotic non-plant species. Predictions are made using a new algorithm [C. Guda and S. Subramaniam (2005) pTARGET [corrected] a new method for predicting protein subcellular localization in eukaryotes. Bioinformatics, 21, 3963–3969], which is primarily based on the occurrence patterns of location-specific protein functional domains in different subcellular locations. We have implemented a relational database, PreCalcDB, to store pre-computed prediction results for all eukaryotic non-plant protein sequences in the public domain that includes about 770 000 entries. Queries can be made by entering protein sequences or by uploading a file containing up to 5000 protein sequences in FASTA format. Prediction results for queries with matching entries in the PreCalcDB will be retrieved instantly; while for the missing ones new predictions will be computed and sent by email. Pre-computed predictions can also be downloaded for complete proteomes of Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila, Mus musculus and Homo sapiens. The server, its documentation and the data are accessible from . |
format | Text |
id | pubmed-1538910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-15389102006-08-18 pTARGET: a web server for predicting protein subcellular localization Guda, Chittibabu Nucleic Acids Res Article The pTARGET web server enables prediction of nine distinct protein subcellular localizations in eukaryotic non-plant species. Predictions are made using a new algorithm [C. Guda and S. Subramaniam (2005) pTARGET [corrected] a new method for predicting protein subcellular localization in eukaryotes. Bioinformatics, 21, 3963–3969], which is primarily based on the occurrence patterns of location-specific protein functional domains in different subcellular locations. We have implemented a relational database, PreCalcDB, to store pre-computed prediction results for all eukaryotic non-plant protein sequences in the public domain that includes about 770 000 entries. Queries can be made by entering protein sequences or by uploading a file containing up to 5000 protein sequences in FASTA format. Prediction results for queries with matching entries in the PreCalcDB will be retrieved instantly; while for the missing ones new predictions will be computed and sent by email. Pre-computed predictions can also be downloaded for complete proteomes of Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila, Mus musculus and Homo sapiens. The server, its documentation and the data are accessible from . Oxford University Press 2006-07-01 2006-07-14 /pmc/articles/PMC1538910/ /pubmed/16844995 http://dx.doi.org/10.1093/nar/gkl093 Text en © The Author 2006. Published by Oxford University Press. All rights reserved |
spellingShingle | Article Guda, Chittibabu pTARGET: a web server for predicting protein subcellular localization |
title | pTARGET: a web server for predicting protein subcellular localization |
title_full | pTARGET: a web server for predicting protein subcellular localization |
title_fullStr | pTARGET: a web server for predicting protein subcellular localization |
title_full_unstemmed | pTARGET: a web server for predicting protein subcellular localization |
title_short | pTARGET: a web server for predicting protein subcellular localization |
title_sort | ptarget: a web server for predicting protein subcellular localization |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538910/ https://www.ncbi.nlm.nih.gov/pubmed/16844995 http://dx.doi.org/10.1093/nar/gkl093 |
work_keys_str_mv | AT gudachittibabu ptargetawebserverforpredictingproteinsubcellularlocalization |