Cargando…
Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation
BACKGROUND: Neuroprotective strategies for prevention of the neuropathological sequelae of traumatic brain injury (TBI) have largely failed in translation to clinical treatment. Thus, there is a substantial need for further understanding the molecular mechanisms and pathways which lead to secondary...
Autores principales: | Leinhase, Iris, Holers, V Michael, Thurman, Joshua M, Harhausen, Denise, Schmidt, Oliver I, Pietzcker, Malte, Taha, Mohy E, Rittirsch, Daniel, Huber-Lang, Markus, Smith, Wade R, Ward, Peter A, Stahel, Philip F |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540436/ https://www.ncbi.nlm.nih.gov/pubmed/16842619 http://dx.doi.org/10.1186/1471-2202-7-55 |
Ejemplares similares
-
Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice
por: Leinhase, Iris, et al.
Publicado: (2007) -
Complement in Human Disease
por: Flierl, Michael A., et al.
Publicado: (2013) -
Role of Complement in Multiorgan Failure
por: Rittirsch, Daniel, et al.
Publicado: (2012) -
Antiphospholipid antibodies harness innate effectors, neutrophils and an alternative pathway of complement, to induce fetal damage
por: Salmon, J, et al.
Publicado: (2003) -
Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis
por: Flierl, Michael A, et al.
Publicado: (2009)