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Identification by Mn(2+) rescue of two residues essential for the proton transfer of tRNase Z catalysis
Thermotoga maritima tRNase Z cleaves pre-tRNAs containing the (74)CCA(76) sequence precisely after the A(76) residue to create the mature 3′ termini. Its crystal structure has revealed a four-layer αβ/βα sandwich fold that is typically found in the metallo-β-lactamase superfamily. The well-conserved...
Autores principales: | Minagawa, Asako, Takaku, Hiroaki, Ishii, Ryohei, Takagi, Masamichi, Yokoyama, Shigeyuki, Nashimoto, Masayuki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540738/ https://www.ncbi.nlm.nih.gov/pubmed/16916792 http://dx.doi.org/10.1093/nar/gkl517 |
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