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Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury

BACKGROUND: Intravenous injection of contrast material is routinely performed in order to differentiate nonaerated lung parenchyma from pleural effusion in critically ill patients undergoing thoracic computed tomography (CT). The aim of the present study was to evaluate the effects of contrast mater...

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Autores principales: Bouhemad, Bélaid, Richecoeur, Jack, Lu, Qin, Malbouisson, Luiz M, Cluzel, Philippe, Rouby, Jean-Jacques
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154113/
https://www.ncbi.nlm.nih.gov/pubmed/12617742
http://dx.doi.org/10.1186/cc1852
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author Bouhemad, Bélaid
Richecoeur, Jack
Lu, Qin
Malbouisson, Luiz M
Cluzel, Philippe
Rouby, Jean-Jacques
author_facet Bouhemad, Bélaid
Richecoeur, Jack
Lu, Qin
Malbouisson, Luiz M
Cluzel, Philippe
Rouby, Jean-Jacques
author_sort Bouhemad, Bélaid
collection PubMed
description BACKGROUND: Intravenous injection of contrast material is routinely performed in order to differentiate nonaerated lung parenchyma from pleural effusion in critically ill patients undergoing thoracic computed tomography (CT). The aim of the present study was to evaluate the effects of contrast material on CT measurement of lung volumes in 14 patients with acute lung injury. METHOD: A spiral thoracic CT scan, consisting of contiguous axial sections of 10 mm thickness, was performed from the apex to the diaphragm at end-expiration both before and 30 s (group 1; n = 7) or 15 min (group 2; n = 7) after injection of 80 ml contrast material. Volumes of gas and tissue, and volumic distribution of CT attenuations were measured before and after injection using specially designed software (Lungview(®); Institut National des Télécommunications, Evry, France). The maximal artifactual increase in lung tissue resulting from a hypothetical leakage within the lung of the 80 ml contrast material was calculated. RESULTS: Injection of contrast material significantly increased the apparent volume of lung tissue by 83 ± 57 ml in group 1 and 102 ± 80 ml in group 2, whereas the corresponding maximal artifactual increases in lung tissue were 42 ± 52 ml and 31 ± 18 ml. CONCLUSION: Because systematic injection of contrast material increases the amount of extravascular lung water in patients with acute lung injury, it seems prudent to avoid this procedure in critically ill patients undergoing a thoracic CT scan and to reserve its use for specific indications.
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spelling pubmed-1541132003-05-06 Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury Bouhemad, Bélaid Richecoeur, Jack Lu, Qin Malbouisson, Luiz M Cluzel, Philippe Rouby, Jean-Jacques Crit Care Research BACKGROUND: Intravenous injection of contrast material is routinely performed in order to differentiate nonaerated lung parenchyma from pleural effusion in critically ill patients undergoing thoracic computed tomography (CT). The aim of the present study was to evaluate the effects of contrast material on CT measurement of lung volumes in 14 patients with acute lung injury. METHOD: A spiral thoracic CT scan, consisting of contiguous axial sections of 10 mm thickness, was performed from the apex to the diaphragm at end-expiration both before and 30 s (group 1; n = 7) or 15 min (group 2; n = 7) after injection of 80 ml contrast material. Volumes of gas and tissue, and volumic distribution of CT attenuations were measured before and after injection using specially designed software (Lungview(®); Institut National des Télécommunications, Evry, France). The maximal artifactual increase in lung tissue resulting from a hypothetical leakage within the lung of the 80 ml contrast material was calculated. RESULTS: Injection of contrast material significantly increased the apparent volume of lung tissue by 83 ± 57 ml in group 1 and 102 ± 80 ml in group 2, whereas the corresponding maximal artifactual increases in lung tissue were 42 ± 52 ml and 31 ± 18 ml. CONCLUSION: Because systematic injection of contrast material increases the amount of extravascular lung water in patients with acute lung injury, it seems prudent to avoid this procedure in critically ill patients undergoing a thoracic CT scan and to reserve its use for specific indications. BioMed Central 2003 2002-12-12 /pmc/articles/PMC154113/ /pubmed/12617742 http://dx.doi.org/10.1186/cc1852 Text en Copyright © 2003 Bouhemad et al., licensee BioMed Central Ltd
spellingShingle Research
Bouhemad, Bélaid
Richecoeur, Jack
Lu, Qin
Malbouisson, Luiz M
Cluzel, Philippe
Rouby, Jean-Jacques
Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title_full Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title_fullStr Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title_full_unstemmed Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title_short Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
title_sort effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154113/
https://www.ncbi.nlm.nih.gov/pubmed/12617742
http://dx.doi.org/10.1186/cc1852
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