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Correction: Functional and molecular characterisation of mammary side population cells

It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared...

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Autores principales: Alvi, Azra J, Clayton, Helen, Joshi, Chirag, Enver, Tariq, Ashworth, Alan, Vivanco, Maria d M, Dale, Trevor C, Smalley, Matthew J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154140/
http://dx.doi.org/10.1186/bcr563
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author Alvi, Azra J
Clayton, Helen
Joshi, Chirag
Enver, Tariq
Ashworth, Alan
Vivanco, Maria d M
Dale, Trevor C
Smalley, Matthew J
author_facet Alvi, Azra J
Clayton, Helen
Joshi, Chirag
Enver, Tariq
Ashworth, Alan
Vivanco, Maria d M
Dale, Trevor C
Smalley, Matthew J
author_sort Alvi, Azra J
collection PubMed
description It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.
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spelling pubmed-1541402003-05-06 Correction: Functional and molecular characterisation of mammary side population cells Alvi, Azra J Clayton, Helen Joshi, Chirag Enver, Tariq Ashworth, Alan Vivanco, Maria d M Dale, Trevor C Smalley, Matthew J Breast Cancer Res Correction It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith. BioMed Central 2003 2002-12-04 /pmc/articles/PMC154140/ http://dx.doi.org/10.1186/bcr563 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Correction
Alvi, Azra J
Clayton, Helen
Joshi, Chirag
Enver, Tariq
Ashworth, Alan
Vivanco, Maria d M
Dale, Trevor C
Smalley, Matthew J
Correction: Functional and molecular characterisation of mammary side population cells
title Correction: Functional and molecular characterisation of mammary side population cells
title_full Correction: Functional and molecular characterisation of mammary side population cells
title_fullStr Correction: Functional and molecular characterisation of mammary side population cells
title_full_unstemmed Correction: Functional and molecular characterisation of mammary side population cells
title_short Correction: Functional and molecular characterisation of mammary side population cells
title_sort correction: functional and molecular characterisation of mammary side population cells
topic Correction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154140/
http://dx.doi.org/10.1186/bcr563
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