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Akt kinases in breast cancer and the results of adjuvant therapy

BACKGROUND: The serine/threonine kinase Akt, or protein kinase B, has recently been a focus of interest because of its activity to inhibit apoptosis. It mediates cell survival by acting as a transducer of signals from growth factor receptors that activate phosphatidylinositol 3-kinase. METHODS: We a...

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Detalles Bibliográficos
Autores principales: Stål, Olle, Pérez-Tenorio, Gizeh, Åkerberg, Linda, Olsson, Birgit, Nordenskjöld, Bo, Skoog, Lambert, Rutqvist, Lars Erik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154147/
https://www.ncbi.nlm.nih.gov/pubmed/12631397