Breast cancer cell lines: friend or foe?

The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

Detalles Bibliográficos
Autores principales: Burdall, Sarah E, Hanby, Andrew M, Lansdown, Mark RJ, Speirs, Valerie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154155/
https://www.ncbi.nlm.nih.gov/pubmed/12631387
Descripción
Sumario:The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

Ejemplares similares