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Cyclin D1 and mammary carcinoma: new insights from transgenic mouse models

Cyclin D1 is one of the most commonly overexpressed oncogenes in breast cancer, with 45–50% of primary ductal carcinomas overexpressing this oncoprotein. Targeted deletion of the gene encoding cyclin D1 demonstrates an essential role in normal mammary gland development while transgenic studies provi...

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Detalles Bibliográficos
Autores principales:	Sutherland, Robert L, Musgrove, Elizabeth A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154565/ https://www.ncbi.nlm.nih.gov/pubmed/11879554 http://dx.doi.org/10.1186/bcr411

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