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Modeling Somatic Evolution in Tumorigenesis

Tumorigenesis in humans is thought to be a multistep process where certain mutations confer a selective advantage, allowing lineages derived from the mutated cell to outcompete other cells. Although molecular cell biology has substantially advanced cancer research, our understanding of the evolution...

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Detalles Bibliográficos
Autores principales: Spencer, Sabrina L, Gerety, Ryan A, Pienta, Kenneth J, Forrest, Stephanie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550273/
https://www.ncbi.nlm.nih.gov/pubmed/16933983
http://dx.doi.org/10.1371/journal.pcbi.0020108