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Modeling Somatic Evolution in Tumorigenesis
Tumorigenesis in humans is thought to be a multistep process where certain mutations confer a selective advantage, allowing lineages derived from the mutated cell to outcompete other cells. Although molecular cell biology has substantially advanced cancer research, our understanding of the evolution...
Autores principales: | Spencer, Sabrina L, Gerety, Ryan A, Pienta, Kenneth J, Forrest, Stephanie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550273/ https://www.ncbi.nlm.nih.gov/pubmed/16933983 http://dx.doi.org/10.1371/journal.pcbi.0020108 |
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