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Recombinant activated protein C: the key is clinical assessment of risk of death, not subset analysis

The PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis) trial demonstrated a 6.1% absolute decrease in mortality with a p value of 0.005. Despite the impressive results of this trial, criticism of the study has targeted various aspects of design, analysis and interp...

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Detalles Bibliográficos
Autor principal: Dellinger, R Phillip
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550791/
https://www.ncbi.nlm.nih.gov/pubmed/16542472
http://dx.doi.org/10.1186/cc3991

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