Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis

INTRODUCTION: Disturbed protein C (PC) pathway homeostasis might contribute to the development of multiple organ failure (MOF) in acute pancreatitis (AP). We therefore evaluated circulating levels of PC and activated protein C (APC), evaluated monocyte deactivation in AP patients, and determined the...

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Detalles Bibliográficos
Autores principales: Lindstrom, Outi, Kylanpaa, Leena, Mentula, Panu, Puolakkainen, Pauli, Kemppainen, Esko, Haapiainen, Reijo, Fernandez, Jose A, Griffin, John H, Repo, Heikki, Petaja, Jari
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550818/
https://www.ncbi.nlm.nih.gov/pubmed/16420659
http://dx.doi.org/10.1186/cc3966

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