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Hyperglycaemia in critically ill patients: marker or mediator of mortality?
Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients....
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550943/ https://www.ncbi.nlm.nih.gov/pubmed/16834760 http://dx.doi.org/10.1186/cc4957 |
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author | Corstjens, Anouk M van der Horst, Iwan CC Zijlstra, Jan G Groeneveld, AB Johan Zijlstra, Felix Tulleken, Jaap E Ligtenberg, Jack JM |
author_facet | Corstjens, Anouk M van der Horst, Iwan CC Zijlstra, Jan G Groeneveld, AB Johan Zijlstra, Felix Tulleken, Jaap E Ligtenberg, Jack JM |
author_sort | Corstjens, Anouk M |
collection | PubMed |
description | Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of hyperglycaemia in critically ill patients, using stringent criteria, approaches 100%. An unambiguous negative correlation between hyperglycaemia and mortality has been described in various groups of critically ill patients. Although the available evidence remains inconsistent, there appears to be a favourable effect of glucose regulation. This effect on morbidity and mortality depends on patient characteristics. To be able to compare results of future studies involving glucose regulation, better definitions of hyperglycaemia (and consequently of normoglycaemia) and patient populations are needed. |
format | Text |
id | pubmed-1550943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15509432006-08-22 Hyperglycaemia in critically ill patients: marker or mediator of mortality? Corstjens, Anouk M van der Horst, Iwan CC Zijlstra, Jan G Groeneveld, AB Johan Zijlstra, Felix Tulleken, Jaap E Ligtenberg, Jack JM Crit Care Review Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of hyperglycaemia in critically ill patients, using stringent criteria, approaches 100%. An unambiguous negative correlation between hyperglycaemia and mortality has been described in various groups of critically ill patients. Although the available evidence remains inconsistent, there appears to be a favourable effect of glucose regulation. This effect on morbidity and mortality depends on patient characteristics. To be able to compare results of future studies involving glucose regulation, better definitions of hyperglycaemia (and consequently of normoglycaemia) and patient populations are needed. BioMed Central 2006 2006-06-27 /pmc/articles/PMC1550943/ /pubmed/16834760 http://dx.doi.org/10.1186/cc4957 Text en Copyright © 2006 BioMed Central Ltd. |
spellingShingle | Review Corstjens, Anouk M van der Horst, Iwan CC Zijlstra, Jan G Groeneveld, AB Johan Zijlstra, Felix Tulleken, Jaap E Ligtenberg, Jack JM Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title | Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title_full | Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title_fullStr | Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title_full_unstemmed | Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title_short | Hyperglycaemia in critically ill patients: marker or mediator of mortality? |
title_sort | hyperglycaemia in critically ill patients: marker or mediator of mortality? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550943/ https://www.ncbi.nlm.nih.gov/pubmed/16834760 http://dx.doi.org/10.1186/cc4957 |
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