Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage

BACKGROUND: Cernunnos-XLF is a nonhomologous end-joining factor that is mutated in patients with a rare immunodeficiency with microcephaly. Several other microcephaly-associated genes such as ASPM and microcephalin experienced recent adaptive evolution apparently linked to brain size expansion in hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Pavlicek, Adam, Jurka, Jerzy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1552050/
https://www.ncbi.nlm.nih.gov/pubmed/16749933
http://dx.doi.org/10.1186/1745-6150-1-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1552050/
https://www.ncbi.nlm.nih.gov/pubmed/16749933
http://dx.doi.org/10.1186/1745-6150-1-15

Ejemplares similares