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Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage

BACKGROUND: Cernunnos-XLF is a nonhomologous end-joining factor that is mutated in patients with a rare immunodeficiency with microcephaly. Several other microcephaly-associated genes such as ASPM and microcephalin experienced recent adaptive evolution apparently linked to brain size expansion in hu...

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Detalles Bibliográficos
Autores principales:	Pavlicek, Adam, Jurka, Jerzy
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1552050/ https://www.ncbi.nlm.nih.gov/pubmed/16749933 http://dx.doi.org/10.1186/1745-6150-1-15

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