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The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway

BACKGROUND: The vanilloid receptor 1 (TRPV1) is critical in the development of inflammatory hyperalgesia. Several receptors including G-protein coupled prostaglandin receptors have been reported to functionally interact with the TRPV1 through a cAMP-dependent protein kinase A (PKA) pathway to potent...

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Detalles Bibliográficos
Autores principales: Vetter, Irina, Wyse, Bruce D, Monteith, Gregory R, Roberts-Thomson, Sarah J, Cabot, Peter J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1553434/
https://www.ncbi.nlm.nih.gov/pubmed/16842630
http://dx.doi.org/10.1186/1744-8069-2-22