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Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7

BACKGROUND: The activation induced T cell specific adapter protein (TSAd), encoded by SH2D2A, interacts with and modulates Lck activity. Several transcript variants of TSAd mRNA exist, but their biological significance remains unknown. Here we examined expression of SH2D2A transcripts in activated C...

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Detalles Bibliográficos
Autores principales:	Granum, Stine, Sundvold-Gjerstad, Vibeke, Dai, Ke-Zheng, Kolltveit, Kristin Melkevik, Hildebrand, Kjersti, Huitfeldt, Henrik S, Lea, Tor, Spurkland, Anne
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1553471/ https://www.ncbi.nlm.nih.gov/pubmed/16839418 http://dx.doi.org/10.1186/1471-2172-7-15

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