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Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms.
EAU is a model of ocular inflammatory disease. EAU resembles another T cell-mediated autoimmune disease--experimental allergic encephalomyelitis--since both have increased expression of MHC class II molecules in the target tissue, can be adoptively transferred by activated CD4+ T cells and are inhib...
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Formato: | Texto |
Lenguaje: | English |
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1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1554436/ https://www.ncbi.nlm.nih.gov/pubmed/1638760 |
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author | Calder, V L Lightman, S L |
author_facet | Calder, V L Lightman, S L |
author_sort | Calder, V L |
collection | PubMed |
description | EAU is a model of ocular inflammatory disease. EAU resembles another T cell-mediated autoimmune disease--experimental allergic encephalomyelitis--since both have increased expression of MHC class II molecules in the target tissue, can be adoptively transferred by activated CD4+ T cells and are inhibited by cyclosporin A. The immunological findings will be compared to find out if the same cellular mechanisms are involved in both diseases. |
format | Text |
id | pubmed-1554436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1992 |
record_format | MEDLINE/PubMed |
spelling | pubmed-15544362007-07-12 Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. Calder, V L Lightman, S L Clin Exp Immunol Research Article EAU is a model of ocular inflammatory disease. EAU resembles another T cell-mediated autoimmune disease--experimental allergic encephalomyelitis--since both have increased expression of MHC class II molecules in the target tissue, can be adoptively transferred by activated CD4+ T cells and are inhibited by cyclosporin A. The immunological findings will be compared to find out if the same cellular mechanisms are involved in both diseases. 1992-08 /pmc/articles/PMC1554436/ /pubmed/1638760 Text en |
spellingShingle | Research Article Calder, V L Lightman, S L Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title | Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title_full | Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title_fullStr | Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title_full_unstemmed | Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title_short | Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms. |
title_sort | experimental autoimmune uveoretinitis (eau) versus experimental allergic encephalomyelitis (eae): a comparison of t cell-mediated mechanisms. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1554436/ https://www.ncbi.nlm.nih.gov/pubmed/1638760 |
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