Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]

INTRODUCTION: Experimental and clinical data show that the oral bisphosphonate clodronate (Bonefos(®)) can inhibit tumor-induced osteoclastic bone resorption. This randomized, double-blind, placebo-controlled, multicenter trial was designed to determine if the addition of oral clodronate to standard...

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Detalles Bibliográficos
Autores principales: Powles, Trevor, Paterson, Alexander, McCloskey, Eugene, Schein, Phil, Scheffler, Bobbi, Tidy, Alwynne, Ashley, Sue, Smith, Ian, Ottestad, Lars, Kanis, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557723/
https://www.ncbi.nlm.nih.gov/pubmed/16542503
http://dx.doi.org/10.1186/bcr1384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557723/
https://www.ncbi.nlm.nih.gov/pubmed/16542503
http://dx.doi.org/10.1186/bcr1384

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