Variation in the RAD51 gene and familial breast cancer

INTRODUCTION: Human RAD51 is a homologue of the Escherichia coli RecA protein and is known to function in recombinational repair of double-stranded DNA breaks. Mutations in the lower eukaryotic homologues of RAD51 result in a deficiency in the repair of double-stranded DNA breaks. Loss of RAD51 func...

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Detalles Bibliográficos
Autores principales: Lose, Felicity, Lovelock, Paul, Chenevix-Trench, Georgia, Mann, Graham J, Pupo, Gulietta M, Spurdle, Amanda B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557738/
https://www.ncbi.nlm.nih.gov/pubmed/16762046
http://dx.doi.org/10.1186/bcr1415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557738/
https://www.ncbi.nlm.nih.gov/pubmed/16762046
http://dx.doi.org/10.1186/bcr1415

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