Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct

GTP hydrolysis catalyzed in the ribosome by a complex of two polypeptide release factors, eRF1 and eRF3, is required for fast and efficient termination of translation in eukaryotes. Here, isothermal titration calorimetry is used for the quantitative thermodynamic characterization of eRF3 interaction...

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Detalles Bibliográficos
Autores principales: Mitkevich, Vladimir A., Kononenko, Artem V., Petrushanko, Irina Yu., Yanvarev, Dmitry V., Makarov, Alexander A., Kisselev, Lev L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557817/
https://www.ncbi.nlm.nih.gov/pubmed/16914449
http://dx.doi.org/10.1093/nar/gkl549

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