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ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency

BACKGROUND: The herpes simplex virus type 1 (HSV-1) ICP0 protein is an E3 ubiquitin ligase, which is encoded within the HSV-1 latency-associated locus. When ICP0 is not synthesized, the HSV-1 genome is acutely susceptible to cellular repression. Reciprocally, when ICP0 is synthesized, viral replicat...

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Detalles Bibliográficos
Autores principales:	Halford, William P, Weisend, Carla, Grace, Jennifer, Soboleski, Mark, Carr, Daniel JJ, Balliet, John W, Imai, Yumi, Margolis, Todd P, Gebhardt, Bryan M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557838/ https://www.ncbi.nlm.nih.gov/pubmed/16764725 http://dx.doi.org/10.1186/1743-422X-3-44

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