Cargando…
Getting to synaptic complexes through systems biology
Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1558000/ https://www.ncbi.nlm.nih.gov/pubmed/16677427 http://dx.doi.org/10.1186/gb-2006-7-4-214 |
_version_ | 1782129430027567104 |
---|---|
author | Jordan, Bryen A Ziff, Edward B |
author_facet | Jordan, Bryen A Ziff, Edward B |
author_sort | Jordan, Bryen A |
collection | PubMed |
description | Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex. |
format | Text |
id | pubmed-1558000 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15580002006-09-02 Getting to synaptic complexes through systems biology Jordan, Bryen A Ziff, Edward B Genome Biol Minireview Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex. BioMed Central 2006 2006-04-27 /pmc/articles/PMC1558000/ /pubmed/16677427 http://dx.doi.org/10.1186/gb-2006-7-4-214 Text en Copyright © 2006 BioMed Central Ltd |
spellingShingle | Minireview Jordan, Bryen A Ziff, Edward B Getting to synaptic complexes through systems biology |
title | Getting to synaptic complexes through systems biology |
title_full | Getting to synaptic complexes through systems biology |
title_fullStr | Getting to synaptic complexes through systems biology |
title_full_unstemmed | Getting to synaptic complexes through systems biology |
title_short | Getting to synaptic complexes through systems biology |
title_sort | getting to synaptic complexes through systems biology |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1558000/ https://www.ncbi.nlm.nih.gov/pubmed/16677427 http://dx.doi.org/10.1186/gb-2006-7-4-214 |
work_keys_str_mv | AT jordanbryena gettingtosynapticcomplexesthroughsystemsbiology AT ziffedwardb gettingtosynapticcomplexesthroughsystemsbiology |