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Getting to synaptic complexes through systems biology

Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes...

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Detalles Bibliográficos
Autores principales: Jordan, Bryen A, Ziff, Edward B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1558000/
https://www.ncbi.nlm.nih.gov/pubmed/16677427
http://dx.doi.org/10.1186/gb-2006-7-4-214
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author Jordan, Bryen A
Ziff, Edward B
author_facet Jordan, Bryen A
Ziff, Edward B
author_sort Jordan, Bryen A
collection PubMed
description Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex.
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spelling pubmed-15580002006-09-02 Getting to synaptic complexes through systems biology Jordan, Bryen A Ziff, Edward B Genome Biol Minireview Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex. BioMed Central 2006 2006-04-27 /pmc/articles/PMC1558000/ /pubmed/16677427 http://dx.doi.org/10.1186/gb-2006-7-4-214 Text en Copyright © 2006 BioMed Central Ltd
spellingShingle Minireview
Jordan, Bryen A
Ziff, Edward B
Getting to synaptic complexes through systems biology
title Getting to synaptic complexes through systems biology
title_full Getting to synaptic complexes through systems biology
title_fullStr Getting to synaptic complexes through systems biology
title_full_unstemmed Getting to synaptic complexes through systems biology
title_short Getting to synaptic complexes through systems biology
title_sort getting to synaptic complexes through systems biology
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1558000/
https://www.ncbi.nlm.nih.gov/pubmed/16677427
http://dx.doi.org/10.1186/gb-2006-7-4-214
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