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The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils

BACKGROUND: Glucocorticoids are used to treat chronic inflammatory diseases such as asthma. Induction of eosinophil apoptosis is considered to be one of the main mechanisms behind the anti-asthmatic effect of glucocorticoids. Glucocorticoid binding to its receptor (GR) can have a dual effect on gene...

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Detalles Bibliográficos
Autores principales:	Janka-Junttila, Mirkka, Moilanen, Eeva, Hasala, Hannele, Zhang, Xianzhi, Adcock, Ian, Kankaanranta, Hannu
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559619/ https://www.ncbi.nlm.nih.gov/pubmed/16834783 http://dx.doi.org/10.1186/1476-9255-3-10

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