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Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients
BACKGROUND: End stage renal disease patients are at risk of Vancomycin-Resistant Enterococcus (VRE) infections. The first reports of VRE isolation were from hemodialysis patients. However, to date, VRE fecal colonization rates as well as associated risk factors in kidney transplant patients have not...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559694/ https://www.ncbi.nlm.nih.gov/pubmed/16923193 http://dx.doi.org/10.1186/1471-2334-6-133 |
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author | Freitas, Maria Cecília S Pacheco-Silva, Alvaro Barbosa, Dulce Silbert, Suzane Sader, Hélio Sesso, Ricardo Camargo, Luis Fernando A |
author_facet | Freitas, Maria Cecília S Pacheco-Silva, Alvaro Barbosa, Dulce Silbert, Suzane Sader, Hélio Sesso, Ricardo Camargo, Luis Fernando A |
author_sort | Freitas, Maria Cecília S |
collection | PubMed |
description | BACKGROUND: End stage renal disease patients are at risk of Vancomycin-Resistant Enterococcus (VRE) infections. The first reports of VRE isolation were from hemodialysis patients. However, to date, VRE fecal colonization rates as well as associated risk factors in kidney transplant patients have not yet been established in prospective studies. METHODS: We collected one or two stool samples from 280 kidney transplant patients and analysed the prevalence of VRE and its associated risk factors. Patients were evaluated according to the post-transplant period: group 1, less than 30 days after transplantation (102 patients), group 2, one to 6 months after transplantation (73 patients) and group 3, more than 6 months after transplantation (105 patients). RESULTS: The overall prevalence rate of fecal VRE colonization was 13.6% (38/280), respectively 13.7% for Group 1, 15.1% for group 2 and 12.4% for group 3. E. faecium and E. faecalis comprised 50% of all VRE isolates. No immunologic variables were clearly correlated with VRE colonization and no infections related to VRE colonization were reported. CONCLUSION: Fecal VRE colonization rates in kidney transplant patients were as high as those reported for other high-risk groups, such as critical care and hemodialysis patients. This high rate of VRE colonization observed in kidney transplant recipients may have clinical relevance in infectious complications. |
format | Text |
id | pubmed-1559694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15596942006-09-05 Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients Freitas, Maria Cecília S Pacheco-Silva, Alvaro Barbosa, Dulce Silbert, Suzane Sader, Hélio Sesso, Ricardo Camargo, Luis Fernando A BMC Infect Dis Research Article BACKGROUND: End stage renal disease patients are at risk of Vancomycin-Resistant Enterococcus (VRE) infections. The first reports of VRE isolation were from hemodialysis patients. However, to date, VRE fecal colonization rates as well as associated risk factors in kidney transplant patients have not yet been established in prospective studies. METHODS: We collected one or two stool samples from 280 kidney transplant patients and analysed the prevalence of VRE and its associated risk factors. Patients were evaluated according to the post-transplant period: group 1, less than 30 days after transplantation (102 patients), group 2, one to 6 months after transplantation (73 patients) and group 3, more than 6 months after transplantation (105 patients). RESULTS: The overall prevalence rate of fecal VRE colonization was 13.6% (38/280), respectively 13.7% for Group 1, 15.1% for group 2 and 12.4% for group 3. E. faecium and E. faecalis comprised 50% of all VRE isolates. No immunologic variables were clearly correlated with VRE colonization and no infections related to VRE colonization were reported. CONCLUSION: Fecal VRE colonization rates in kidney transplant patients were as high as those reported for other high-risk groups, such as critical care and hemodialysis patients. This high rate of VRE colonization observed in kidney transplant recipients may have clinical relevance in infectious complications. BioMed Central 2006-08-22 /pmc/articles/PMC1559694/ /pubmed/16923193 http://dx.doi.org/10.1186/1471-2334-6-133 Text en Copyright © 2006 Freitas et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Freitas, Maria Cecília S Pacheco-Silva, Alvaro Barbosa, Dulce Silbert, Suzane Sader, Hélio Sesso, Ricardo Camargo, Luis Fernando A Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title | Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title_full | Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title_fullStr | Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title_full_unstemmed | Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title_short | Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients |
title_sort | prevalence of vancomycin-resistant enterococcus fecal colonization among kidney transplant patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559694/ https://www.ncbi.nlm.nih.gov/pubmed/16923193 http://dx.doi.org/10.1186/1471-2334-6-133 |
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