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Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression

BACKGROUND: Cyclooxygenase (COX) is the rate-limiting enzyme that catalyzes the formation of prostaglandins. The inducible isoform of COX (COX-2) is highly expressed in aggressive metastatic breast cancers and may play a critical role in cancer progression (i.e. growth and metastasis). However, the...

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Detalles Bibliográficos
Autores principales:	Larkins, Teri L, Nowell, Marchele, Singh, Shailesh, Sanford, Gary L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559713/ https://www.ncbi.nlm.nih.gov/pubmed/16831226 http://dx.doi.org/10.1186/1471-2407-6-181

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