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The DNA polymerase activity of Pol ε holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts

BACKGROUND: DNA polymerase ε (Pol ε) is involved in DNA replication, repair, and cell-cycle checkpoint control in eukaryotic cells. Although the roles of replicative Pol α and Pol δ in chromosomal DNA replication are relatively well understood and well documented, the precise role of Pol ε in chromo...

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Detalles Bibliográficos
Autores principales:	Shikata, Koh, Sasa-Masuda, Taro, Okuno, Yukiko, Waga, Shou, Sugino, Akio
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560149/ https://www.ncbi.nlm.nih.gov/pubmed/16925818 http://dx.doi.org/10.1186/1471-2091-7-21

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