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Angiostatin generating capacity and anti-tumour effects of D-penicillamine and plasminogen activators

BACKGROUND: Upregulation of endogenous angiostatin levels may constitute a novel anti-angiogenic, and therefore anti-tumor therapy. In vitro, angiostatin generation is a two-step process, starting with the conversion of plasminogen to plasmin by plasminogen activators (PAs). Next, plasmin excises an...

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Detalles Bibliográficos
Autores principales:	de Groot-Besseling, Renate RJ, Ruers, Theo JM, Lamers-Elemans, Iris L, Maass, Cathy N, de Waal, Robert MW, Westphal, Johan R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560151/ https://www.ncbi.nlm.nih.gov/pubmed/16753063 http://dx.doi.org/10.1186/1471-2407-6-149

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