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Role of common human TRIM5α variants in HIV-1 disease progression
BACKGROUND: The retroviral restriction factor tripartite motif protein (TRIM)5α, is characterized by marked amino acid diversity among primates, including specific clusters of residues under positive selection. The identification of multiple non-synonymous changes in humans suggests that TRIM5α vari...
Autores principales: | Goldschmidt, Valérie, Bleiber, Gabriela, May, Margaret, Martinez, Raquel, Ortiz, Millàn, Telenti, Amalio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560158/ https://www.ncbi.nlm.nih.gov/pubmed/16925802 http://dx.doi.org/10.1186/1742-4690-3-54 |
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