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Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

BACKGROUND: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread occurrence in cancer genome could inactivate many cellular pathways including DNA repair, cell cycle control, apoptosis, cell adherence, and detoxification. The abnormal promoter methylation might be a...

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Detalles Bibliográficos
Autores principales: Yang, Hui-Juan, Liu, Vincent WS, Wang, Yue, Tsang, Percy CK, Ngan, Hextan YS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560388/
https://www.ncbi.nlm.nih.gov/pubmed/16928264
http://dx.doi.org/10.1186/1471-2407-6-212