Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line

BACKGROUND: Bcl-2 and Bcl-XL are anti-apoptotic paralogues that inhibit apoptosis elicited by a wide variety of stimuli, and play critical roles in cancer development and resistance to treatment. Many clinical studies have indicated that expression of these anti-apoptotic proteins in tumours is asso...

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Detalles Bibliográficos
Autores principales: Fiebig, Aline A, Zhu, Weijia, Hollerbach, Catherine, Leber, Brian, Andrews, David W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560389/
https://www.ncbi.nlm.nih.gov/pubmed/16928273
http://dx.doi.org/10.1186/1471-2407-6-213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560389/
https://www.ncbi.nlm.nih.gov/pubmed/16928273
http://dx.doi.org/10.1186/1471-2407-6-213

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