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Allele Frequency Matching Between SNPs Reveals an Excess of Linkage Disequilibrium in Genic Regions of the Human Genome
Significant interest has emerged in mapping genetic susceptibility for complex traits through whole-genome association studies. These studies rely on the extent of association, i.e., linkage disequilibrium (LD), between single nucleotide polymorphisms (SNPs) across the human genome. LD describes the...
Autores principales: | Eberle, Michael A, Rieder, Mark J, Kruglyak, Leonid, Nickerson, Deborah A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560400/ https://www.ncbi.nlm.nih.gov/pubmed/16965180 http://dx.doi.org/10.1371/journal.pgen.0020142 |
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