Malaria pigment paralyzes dendritic cells

The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, has now been clearly shown to mediate immunosuppression by inhibiting dendritic cell ac...

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Detalles Bibliográficos
Autores principales: Urban, Britta C, Todryk, Stephen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1561485/
https://www.ncbi.nlm.nih.gov/pubmed/16620370
http://dx.doi.org/10.1186/jbiol37
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author Urban, Britta C
Todryk, Stephen
author_facet Urban, Britta C
Todryk, Stephen
author_sort Urban, Britta C
collection PubMed
description The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, has now been clearly shown to mediate immunosuppression by inhibiting dendritic cell activity.
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spelling pubmed-15614852006-09-08 Malaria pigment paralyzes dendritic cells Urban, Britta C Todryk, Stephen J Biol Minireview The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, has now been clearly shown to mediate immunosuppression by inhibiting dendritic cell activity. BioMed Central 2006 2006-04-12 /pmc/articles/PMC1561485/ /pubmed/16620370 http://dx.doi.org/10.1186/jbiol37 Text en Copyright © 2006 BioMed Central Ltd
spellingShingle Minireview
Urban, Britta C
Todryk, Stephen
Malaria pigment paralyzes dendritic cells
title Malaria pigment paralyzes dendritic cells
title_full Malaria pigment paralyzes dendritic cells
title_fullStr Malaria pigment paralyzes dendritic cells
title_full_unstemmed Malaria pigment paralyzes dendritic cells
title_short Malaria pigment paralyzes dendritic cells
title_sort malaria pigment paralyzes dendritic cells
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1561485/
https://www.ncbi.nlm.nih.gov/pubmed/16620370
http://dx.doi.org/10.1186/jbiol37
work_keys_str_mv AT urbanbrittac malariapigmentparalyzesdendriticcells
AT todrykstephen malariapigmentparalyzesdendriticcells

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