Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function

BACKGROUND: Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens. Significant depression of the host's systemic immune response to both concurr...

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Detalles Bibliográficos
Autores principales: Millington, Owain R, Di Lorenzo, Caterina, Phillips, R Stephen, Garside, Paul, Brewer, James M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1561486/
https://www.ncbi.nlm.nih.gov/pubmed/16611373
http://dx.doi.org/10.1186/jbiol34

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