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Regulators of kinesin involved in polarized trafficking and axon outgrowth

Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse...

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Detalles Bibliográficos
Autores principales: Luo, Shuo, Nonet, Michael L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1561583/
https://www.ncbi.nlm.nih.gov/pubmed/16732897
http://dx.doi.org/10.1186/jbiol41
Descripción
Sumario:Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.