Incorporating background frequency improves entropy-based residue conservation measures

BACKGROUND: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may correlate with structurally or functionally important residues. However, amino acid background frequencies are usually not ta...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Samudrala, Ram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562451/
https://www.ncbi.nlm.nih.gov/pubmed/16916457
http://dx.doi.org/10.1186/1471-2105-7-385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562451/
https://www.ncbi.nlm.nih.gov/pubmed/16916457
http://dx.doi.org/10.1186/1471-2105-7-385

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