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Incorporating background frequency improves entropy-based residue conservation measures
BACKGROUND: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may correlate with structurally or functionally important residues. However, amino acid background frequencies are usually not ta...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562451/ https://www.ncbi.nlm.nih.gov/pubmed/16916457 http://dx.doi.org/10.1186/1471-2105-7-385 |