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E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression
The High Mobility Group protein HMGA2 is a nuclear architectural factor that plays a critical role in a wide range of biological processes including regulation of gene expression, embryogenesis and neoplastic transformation. Several studies are trying to identify the mechanisms by which HMGA2 protei...
Autores principales: | Fedele, Monica, Pierantoni, Giovanna Maria, Visone, Rosa, Fusco, Alfredo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563461/ https://www.ncbi.nlm.nih.gov/pubmed/16914062 http://dx.doi.org/10.1186/1747-1028-1-17 |
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